Aurora B expression correlates with aggressive behaviour in glioblastoma multiforme
نویسندگان
چکیده
منابع مشابه
Glioblastoma Multiforme in Children, A Case-Report
ABSTRACT: Glioblastoma multiforme is the most malignant primary brain tumor .It usually occurs in the 5th and 6th decades of life and is rare in childern. In this paper a case of glioblastoma multiforme is reported in a ten year - old child who presented with two week's history of headache with no neurological defect.C.T scan revealed å right frontal mass with massive surrounding oedema. He w...
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One of the most common type of primary brain tumors in adults is the glioblastoma multiforme (GBM) (World Health Organization grade IV astrocytoma). It is the most common malignant and aggressive form of glioma and it is among the most lethal ones. Poly (ADP-ribose) polymerase 1 (PARP-1) gene, located to 1q42, plays an important role for the efficient maintenance of genome integrity. PARP-1 pro...
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Peroxisome proliferator-activated receptor γ coactivator 1α (PGC1α) is a key modulator of mitochondrial biogenesis. It is a coactivator of multiple transcription factors and regulates metabolic processes. However, little is known about the expression and function of PGC1α in glioblastoma multiforme (GBM), the most prevalent and invasive type of brain tumor. The purpose of the present study was ...
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PURPOSE Treatment of glioblastoma multiforme (GBM) continues to pose a significant therapeutic challenge, with most tumors recurring within the previously irradiated tumor bed. To improve outcomes, we must be able to identify and treat resistant cell populations. Rad51, an enzyme involved in homologous recombinational repair, leads to increased resistance of tumor cells to cytotoxic treatments ...
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Background & Aim: Glioblastoma multiforme (GBM), the highest grade glioma (grade IV), is the most malignant form of astrocytoma in adults. This study aimed at evaluating the relationship between demographic, clinical and medical factors with GBM outcome. Methods & Materials/Patients: Through a cross-sectional design, 58 patients with newly diagnosed GBM were studied from 1999 to 2015 in Guil...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 2006
ISSN: 0021-9746
DOI: 10.1136/jcp.2006.036806